QTc Prolongation in COVID-19 Patients Using Chloroquine

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Prophylactic Effect of Chloroquine and Hydroxy chloroquine in COVID-19 Treatment

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which threatens human health and public safety.Hydroxychloroquine (HCQ) is an anti-malaria drug; its antiviral properties are controversial,and some in vitr...

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There have been only two previous reports of paroxetine-induced corrected QT (QTc) prolongation on electrocardiogram (ECG). Here, we report a 43-year-old woman with QTc prolongation (476 ms). She had taken 50 mg of paroxetine for 17 days. Three days after discontinuation of paroxetine, QTc returned to within the normal limits (396 ms). Paroxetine blocks the human ether-a-go-go-related gene (HER...

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Prolongation of the QTc interval in patients with cirrhosis

and in many congenital and acquired conditions as cardiac disease, electrolyte abnormalities, and many commonly used drugs. Additionally, acquired prolongation of QT interval has been documented in alcoholic liver disease, cirrhosis and liver failure. Liver transplantation in the latter group has been shown to reverse this anomaly. The QT prolongation was found to be independent of the etiology...

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Frequency of QTc prolongation in patients with hemorrhagic stroke.

BACKGROUND Acute cerebral events play an important role in generating autonomic imbalance especially cardiac rhythm disturbances. This forms the basis of significant lethal abnormalities of heart rate and rhythm like QTc prolongation, ventricular fibrillation, asystole, and ultimately death. This study was conducted to determine the frequency of QTc prolongation in patients presenting with acut...

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ژورنال

عنوان ژورنال: Cardiovascular Toxicology

سال: 2021

ISSN: 1530-7905,1559-0259

DOI: 10.1007/s12012-020-09621-2